6. Consider the allele variations in MHC I and II genes. If there are about 1,700 different MHCI alleles, only 2 DRα alleles and 860 DRβ alleles, this suggests that there are (in terms of differences that affect the antigen binding properties) _______.

Question 6
6. Consider the allele variations in MHC I and II genes. If there are about 1,700 different MHCI alleles, only 2 DRα alleles and 860 DRβ alleles, this suggests that there are (in terms of differences that affect the antigen binding properties) _______.
 
 
  • roughly twice as many different MHC IC presenting proteins as there are different MHC II DRαβ dimers

     

  • roughly equal numbers of different MHC IC presenting proteins and different MHC II DRαβ dimers

     

  • roughly half as many different MHC IC presenting proteins as there are different MHC II DRαβ dimers

     

  • There’s no way to tell without knowing the number of different β microglobulin alleles.
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